Relapsing after quitting cocaine is not simply a matter of willpower — it reflects physical changes in the brain, according to new research. Scientists have found that repeated cocaine use reshapes ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring and impulse control, not drug-specific traits.

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that ...

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

An international research team led by the Universitat Jaume I (UJI) has shown that the cerebellum, contrary to what was thought, fulfils functions that go beyond the motor sphere and can be ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

People taking GLP-1 drugs often talk about “food noise” vanishing: the constant mental chatter about food that dominated thei ...

Al-Aly and his colleagues found that people starting the GLP-1 drugs had lower risks of developing addiction to multiple ...

People struggling with many addictions, ranging from opioids to gambling, are reporting similar experiences in clinics, on ...