Plant Physiology, Vol. 140, No. 2 (Feb., 2006), pp. 512-527 (16 pages) The eukaryotic genome is duplicated exactly once per cell division cycle. A strategy that limits every replication origin to a ...

Metazoan cells contain cis-acting DNA sequences, called replicators, that do not share a single consensus DNA sequence but are required for the initiation of DNA replication. Instead of a single ...

Balancing act of a leading strand DNA polymerase-specific domain and its exonuclease domain promotes genome-wide sister replication fork symmetry. Meng X, Claussin C, Regan-Mochrie G, Whitehouse I, ...

Undergraduate biology students could be forgiven for thinking that scientists have DNA replication all figured out. After all, textbooks present the models of replication so matter-of-factly that it's ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...