In a recent study published in the Molecular Psychiatry journal, researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing ...

Wound healing is a multistep biological process involving inflammation, tissue formation, and remodeling. While inflammation is essential for clearing debris and recruiting repair cells, excessive or ...

A Signaling Nexus for Both Good and Ill, It’s Pathways of Pathogenic and Therapeutic Importance Are Still Being Identified A recent paradigm shift in medicine started with the finding that several ...

First-in-class clinical trial in dry AMD with new drug specifically designed to inhibit inflammasome activation in the eye and to be administered locally via a newly designed sustained release implant ...

NEWTON, Mass.--(BUSINESS WIRE)--Inflammasome Therapeutics (https://www.inflam.com/), a clinical-stage biotech company developing novel, first-in-class dual ...

A study out of the University of North Carolina at Chapel Hill has unveiled new insights into the inflammatory processes behind periodontitis, a common and debilitating gum disease. Research conducted ...

(Nanowerk News) Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of ...

Research on the diversity of T cell receptor repertoire in the process of malignant transformation of HBV chronic infection. This is an ASCO Meeting Abstract from the 2017 ASCO Annual Meeting I. This ...

This study was collaboratively performed by Dr. Shu-Hong Yu, Dr. Long-Ping Wen, and Dr. Kun Qu from the University of Science and Technology of China, with Professor Yang Lu from the Hefei University ...

The paper: S. Mariathasan et al., "Cryopyrin activates the inflammasome in response to toxins and ATP," Nature, 440:228-32, 2006. (Cited in 121 papers) The finding: By observing mice deficient in the ...