In the embryonic kidney, three types of precursor cells, nephron progenitor cells, ureteric buds, and interstitial progenitor cells, interact to form three-dimensional structures of the kidney.

Joint research, led by Kumamoto University in Japan, has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. ADPKD is a ...

A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

Chronic kidney disease affects 1 in 9 Americans and more than 300 million persons worldwide. Of these millions, approximately 2.5% have end-stage kidney failure and require treatment with dialysis or ...

In the embryonic kidney, three types of precursor cells interact with each other to form a three-dimensional structure. Previous studies successfully induced nephron structures via nephron progenitors ...