In this free webinar, learn strategies for efficiently synthesizing and optimizing PROTACs and RIPTACs, including isomer separation and tuning linkers, warheads and E3 ligase ligands. The featured ...

Fruit ripening determines both food quality and postharvest losses worldwide, yet the molecular mechanisms controlling this process remain incompletely understood.

Scientists created a definitive E3 ligase atlas, resolving inconsistencies and enabling better disease research and drug ...

STAT6 degradation is expected to provide a clinical benefit for patients with Type 2 inflammatory diseases, including asthma.

Mutations in a protein called KRAS fuel some of the most lethal cancers. Designing drugs to disable KRAS has proved ...

CBL-B is a RING-type E3 ubiquitin ligase that acts as a negative regulator of T-cell activation, contributing to immune homeostasis by limiting excessive immune responses. In cancer, however, this ...

The fireside chat will be webcast live and may be viewed via a link in the Investors section of the Nurix website. The archived webcast will be available for 30 days after the event.

WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body. Published in Cell, the ...

Enrolling Phase 2 DAYBreak CLL-201 bexobrutideg trial designed to support Accelerated Approval in relapsed/refractory chronic lymphocytic ...

Cells rely on tiny molecules called microRNAs to tune which genes are active and when. Cells must carefully control the ...

Cell function is significantly influenced by a process called ubiquitination, in which molecules are selected for elimination ...