Cell senescence — a state of irreversible cell-growth arrest — has important physiological functions and is a key driver of ageing. The articles in this Focus explore the molecular mechanisms that ...

Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms and the ...

Cellular senescence is a state where cells permanently stop dividing but remain metabolically active, often in response to stress or damage. Senescent cells are known to play a key role in wound ...

Microplastics turned up in every human bile sample tested and pushed duct cells toward mitochondrial dysfunction and ...

Now, in a study published March 30 in Cell Chemical Biology, UB scientists have shed light on one such stressor, showing that ...

Cellular senescence is marked by irreversible cell cycle arrest, lysosomal changes, regulatory protein expression, and SASP activation, impacting tissue health and repair. Cellular senescence is a ...

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging. Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap ...

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which ...